Anthropology and Human Genetics

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Computational Tools

  • powsimR


    Power analysis is essential to optimize the design of RNA-seq experiments and to assess and compare the power to detect differentially expressed genes in RNA-seq data. PowsimR is a flexible tool to simulate and evaluate differential expression from bulk and especially single-cell RNA-seq data making it suitable for a priori and posterior power analyses. more

  • zUMIs


    RNA sequencing is increasingly performed with less starting material and at a higher sample throughput, e.g. to analyse single-cell transcriptomes. In this context, unique molecular identifiers (UMIs) are used to reduce amplification noise and sample-specific barcodes are used to track libraries. Here, we present a fast and flexible pipeline to process data from such RNA-seq protocols. more